Dactolisib (BEZ235)

Product Name: Dactolisib (BEZ235)
Description: Dactolisib, also known as BEZ235, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BEZ235 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling path
CAS NO: 114899-80-8 Product: Ecteinascidin 770
Synonym: BEZ235; BEZ-235; BEZ 235; NVPBEZ235; Dactolisib.
IUPAC Chemical Name: 2-Methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile.
In ChiKey: JOGKUKXHTYWRGZ-UHFFFAOYSA-NTryptophan Hydroxylase inhibitors
SMILE Code: CC(C1=CC=C(N(C2=C3C=NC4=CC=C(C5=CC6=CC=CC=C6N=C5)C=C24)C(N3C)=O)C=C1)(C)C#N
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22116522
Chemical Formulaļ¼šC30H23N5O
ExactMass: 469.19026
Molecular Weight: 469.54
Elemental Analysis: C, 76.74; H, 4.94; N, 14.92; O, 3.41

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