E-4177

Product Name: E-4177
Description: E-4177 is an angiotensin type 1 receptor antagonist potentially for the treatment of hypertension. In rat adrenal cortex and liver, E4177 competitively inhibited the specific binding of 125I-[Sar1,Ile8]Ang II, with IC50 being (5.2 +/- 1.0) x 10(-8) M for
CAS NO: 836620-48-5 Product: AS1842856
Synonym: E-4177; E-4177; E4177.
IUPAC Chemical Name: 4-((2-cyclopropyl-7-methyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)-[1,1-biphenyl]-2-carboxylic acid
In ChiKey: VWWMGPCUZVOLLK-UHFFFAOYSA-NInsulin Receptor inhibitors
SMILE Code: O=C(C1=CC=CC=C1C2=CC=C(CN3C(C4CC4)=NC5=C(C)C=CN=C53)C=C2)O
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22118066
Chemical Formulaļ¼šC24H21N3O2
ExactMass: 383.1634
Molecular Weight: 383.451
Elemental Analysis: C, 75.18; H, 5.52; N, 10.96; O, 8.34

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