EAI045 new featured

Product Name: EAI045 new featured
Description: EAI045 ia a potent and selective EGFR inhbitor. EAI045 targets selected drug-resistant EGFR mutants but spares the wild-type receptor. EAI045 inhibits L858R/T790M-mutant EGFR with low-nanomolar potency in biochemical assays.
CAS NO: 918348-67-1 Product: BMS-779788
Synonym: EAI045; EAI-045; EAI 045.
IUPAC Chemical Name: 2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
In ChiKey: YTUFHOKUFOQRDF-UHFFFAOYSA-NTGF-beta_Smad inhibitors
SMILE Code: O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22118674
Chemical Formula:C19H14FN3O3S
ExactMass: 383.074
Molecular Weight: 383.3974
Elemental Analysis: C, 59.52; H, 3.68; F, 4.96; N, 10.96; O, 12.52; S, 8.36

About author

Leave a reply

You must be logged in to post a comment.