GDC-0152

Product Name: GDC-0152
Description: GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity. Smac mimetic GDC-0152 binds to the Smac binding groove on IAPs, including the direct caspas
CAS NO: 216450-65-6 Product: Sophoflavescenol
Synonym: GDC0152; GDC0152; GDC 0152.
IUPAC Chemical Name: (S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-N-(4-phenyl-1,2,3-thiadiazol-5-yl)pyrrolidine-2-carboxamide
In ChiKey: Sirtuin inhibitors
SMILE Code: O=C([[email protected]]1N(C([[email protected]](C2CCCCC2)NC([[email protected]@H](NC)C)=O)=O)CCC1)NC3=C(C4=CC=CC=C4)N=NS3
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22123065
Chemical Formulaļ¼šC25H34N6O3S
ExactMass: 498.24131
Molecular Weight: 498.64
Elemental Analysis: C, 60.22; H, 6.87; N, 16.85; O, 9.63; S, 6.43

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