GDC-0349

Product Name: GDC-0349
Description: GDC-0349 is a small molecule anticaner drug candidate, being developed by Genentech. As of July 2012, Genentech has filed phase I trial of GDC-0349 for evaluating the Safety and Tolerability of GDC-0349 in Patients With Locally Advanced or Metastatic Soli
CAS NO: 1343403-10-0 Product: Epoxymicheliolide
Synonym: GDC0349; GDC 0349; GDC-0349 ; RG7603.
IUPAC Chemical Name: (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea
In ChiKey: Topoisomerase inhibitors
SMILE Code: O=C(NC1=CC=C(C2=NC(N3[[email protected]@H](C)COCC3)=C4C(CN(C5COC5)CC4)=N2)C=C1)NCC
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22123095
Chemical Formulaļ¼šC24H32N6O3
ExactMass: 452.25359
Molecular Weight: 452.55
Elemental Analysis: C, 63.70; H, 7.13; N, 18.57; O, 10.61

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