GDC-0425

Product Name: GDC-0425
Description: GDC-0425, also known as RG7602. is an oral, selective Chk1 inhibitor. GDC-0425 enhances gemcitabine (gem) efficacy in tumor xenograft models. Greater chemopotentiation is observed in cancer cell lines lacking p53 activity. GDC-0425 blocks the function of
CAS NO: 55056-80-9 Product: Protodioscin
Synonym: GDC0425; GDC-0425; GDC 0425; RG7602; RG-7602; RG 7602.
IUPAC Chemical Name: 5-((1-ethylpiperidin-4-yl)oxy)-9H-pyrrolo[2,3-b:5,4-c]dipyridine-6-carbonitrile
In ChiKey: Wee1 inhibitors
SMILE Code: N#CC1=NC=C2C(C3=CC=CN=C3N2)=C1OC4CCN(CC)CC4
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site:Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22123096
Chemical Formula:C18H19N5O
ExactMass: 321.159
Molecular Weight: 321.384
Elemental Analysis: C, 67.27; H, 5.96; N, 21.79; O, 4.98

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