JNJ-10181457

Product Name: JNJ-10181457
Description: JNJ-10181457 is a histamine H3 receptor antagonist (pKi values are 8.15 and 8.93 for rat and human H3 receptors respectively). It increases extracellular norepinephrine and acetylcholine levels in rat frontal cortex but does not stimulate dopamine release
CAS NO: 212391-58-7 Product: PP58
Synonym: JNJ-10181457; JNJ10181457; JNJ 10181457.
IUPAC Chemical Name: 4-(3-(4-(Piperidinyl)but-1-ynyl)benzyl)morpholine
In ChiKey: Carbonic Anhydrase inhibitors
SMILE Code: N1(CC2=CC=CC(C#CCCN3CCCCC3)=C2)CCOCC1
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22128028
Chemical Formulaļ¼šC20H28N2O
ExactMass: 312.22016
Molecular Weight: 312.45
Elemental Analysis: C, 76.88; H, 9.03; N, 8.97; O, 5.12

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