JNJ16259685

Product Name: JNJ16259685
Description: JNJ16259685 is a potent, non-competitive mGlu1 antagonist (Ki = 0.34 nM). JNJ16259685 inhibits glutamate-induced Ca2+ response at the human mGlu1 receptor with an IC50 value of 0.55 nM. JNJ16259685 is selective over mGlu5 (> 400-fold) and displays no a
CAS NO: 1210608-43-7 Product: PIM447
Synonym: JNJ16259685; JNJ 16259685; JNJ-16259685.
IUPAC Chemical Name: (3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl)(4-methoxycyclohexyl)methanone
In ChiKey: QOTAQTRFJWLFCR-UHFFFAOYSA-NElastase inhibitors
SMILE Code: O=C(C1=CC=C2N=C3C(CCCO3)=CC2=C1)C4CCC(OC)CC4
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22128166
Chemical Formulaļ¼šC20H23NO3
ExactMass: 325.1678
Molecular Weight: 325.41
Elemental Analysis: C, 73.82; H, 7.12; N, 4.30; O, 14.75

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