L685458 featured

Product Name: L685458 featured
Description: L685458 is a potent and selective γ -secretase inhibitor (IC50 = 17 nM) that displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. L685458 also exhibits equal potency for inhibition of A β 40 and A β 42 peptides (IC50
CAS NO: 1268798 Product: Cynaroside
Synonym: L685458; L-685458; L 685458; L685,458, L-685,458; L 685,458
IUPAC Chemical Name: tert-butyl ((2S,3R,5R)-6-(((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-5-benzyl-3-hydroxy-6-oxo-1-phenylhexan-2-yl)carbamate.
In ChiKey: Vitamin D Related inhibitors
SMILE Code: O=C(OC(C)(C)C)N[[email protected]]([[email protected]](O)C[[email protected]@H](CC1=CC=CC=C1)C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CC2=CC=CC=C2)C(N)=O)=O)=O)CC3=CC=CC=C3
Appearance: Solid powder
Purity: 0.98
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22131424/
Chemical Formula:C39H52N4O6
ExactMass: 672.38869
Molecular Weight: 672.85
Elemental Analysis: C, 69.62; H, 7.79; N, 8.33; O, 14.27