Product Name :
SKF96067
Description:
SKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase.
CAS:
115607-61-9
Molecular Weight:
334.41
Formula:
C21H22N2O2
Chemical Name:
1-8-methoxy-4-[(2-methylphenyl)amino]quinolin-3-ylbutan-1-one
Smiles :
CC1=CC=CC=C1NC1C2=CC=CC(OC)=C2N=CC=1C(=O)CCC
InChiKey:
MAVJDLHBPIXVJL-UHFFFAOYSA-N
InChi :
InChI=1S/C21H22N2O2/c1-4-8-18(24)16-13-22-21-15(10-7-12-19(21)25-3)20(16)23-17-11-6-5-9-14(17)2/h5-7,9-13H,4,8H2,1-3H3,(H,22,23)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
SKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase.|Product information|CAS Number: 115607-61-9|Molecular Weight: 334.41|Formula: C21H22N2O2|Chemical Name: 1-8-methoxy-4-[(2-methylphenyl)amino]quinolin-3-ylbutan-1-one|Smiles: CC1=CC=CC=C1NC1C2=CC=CC(OC)=C2N=CC=1C(=O)CCC|InChiKey: MAVJDLHBPIXVJL-UHFFFAOYSA-N|InChi: InChI=1S/C21H22N2O2/c1-4-8-18(24)16-13-22-21-15(10-7-12-19(21)25-3)20(16)23-17-11-6-5-9-14(17)2/h5-7,9-13H,4,8H2,1-3H3,(H,22,23)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.BHQ-880 Activator |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|SKF96067 inhibits K+-stimulated ATPase activity competitively with respect to the activating action K+, with a Ki value of 0.Congo Red custom synthesis 39 ± 0.PMID:32798199 05 μM. SKF96067 also inhibits hydrogen ion transport. SKF96067 inhibits ATPase activity with an IC50 value of 60 ± 10 μM at pH 7.0, in the presence of 100 mM NaCl and 1 mM KCl.|References:|Keeling DJ, et al. SK&F 96067 is a reversible, lumenally acting inhibitor of the gastric (H+ + K+)-ATPase. Biochem Pharmacol. 1991 Jun 21;42(1):123-30.Products are for research use only. Not for human use.|
