L and neurotrauma ICUs involving February 2002 and September 2006. Prior to March 2004 the general ITU made use of PPIs for all sufferers as gastric acid prophylaxis, as well as the neurotrauma ITU made use of PPIs for only patients at high threat of GI ulceration. Following instigation of ventilator care bundles in March 2004 each units gave PPIs to all ventilated sufferers. The incidence of C. difficile toxin-positive samples along with the variety of doses of PPI applied each month had been compared for just before and after this time period. The use of antibiotics was also compared in between the two units more than the time period to exclude this as a confounding variable. Final results We identified 92 C. difficile-positive faecal samples through the 57-month period from February 2002 to September 2006. This averaged 1.61 circumstances per month. The common ITU (ITU2) presented 49 instances (53.two ), along with the neurotrauma ITU (ITU3) 43 circumstances (46.8 ). In February 2002, PPI usage was infrequent within the ITU3, but additional popular in ITU2. The C. difficile prices had been also larger in ITU2 than in ITU3. PPI usage elevated in ITU3 until, around the instigation of your ventilator care bundle, PPIs were applied for all patients from March 2004. Our preliminary PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20799915 information demonstrate an increase in C. difficile prices in ITU3, to meet the rates of ITU2, in the very same time as PPI usage was improved (Figure 1). The ITUs back onto each other and share precisely the same medical and nursing employees. Antibiotic usage was similar across both units with regards to cephalosporins, meropenem and pipracillin/tazobactam. Conclusion C. difficile rates have PF-06687859 web remained fairly steady around the general ITU (ITU2) but showed a significant improve on theP147 A study of enteral tube feeding in critically ill patientsA Holdsworth, T Rahman St George’s Hospital, London, UK Essential Care 2007, 11(Suppl two):P147 (doi: 10.1186/cc5307) Introduction For critically ill patients unable to consume, enteral tube feeding (ETF) is definitely the preferred mode of feeding. The study aimed to investigate the quantity of enteral feed obtained by individuals on ICU in a busy London Teaching Hospital, the efficiency of initiation of feeding, and probable motives for the failure with the above. Procedures A potential observational study was carried out more than 1 month on sufferers admitted to a basic and cardiothoracic ICU, who received ETF. Baseline data which includes age, cause for admission and illness severity score (SOFA) have been documented. Length of time from admission to begin of feeding was noted, plus the volume of feed delivered to sufferers was recorded. The quantity of calories delivered to the patient was compared with all the patient’s perfect nutritional requirement (determined by the ICU ETF protocol). Feeding interruptions were also recorded.SCritical CareMarch 2007 Vol 11 Suppl27th International Symposium on Intensive Care and Emergency MedicineFigure 1 (abstract P148)involving altering tracheostomy (suggesting repeat procedures) and subsequent difficulty swallowing. One patient inside this group subsequently created a tracheal stenosis. See Table 1. Conclusion We found the percentage of patients reporting swallowing troubles post percutaneous tracheostomy (PCT) (Portex Blue Line Ultra tracheostomy tube) to become greater than a single would expect. This might be confounded by neurological injury necessitating the need to have for a PCT, but we feel this may be an region of concern meriting additional investigation given frequent PCT in ICU practice.P150 Intestinal corticotropin-releasing issue is decreased in shocked trauma.