Elationship at haemoglobin levels under 9 g/dl.P410 Transfusion from male-only vs female donors in critically ill recipients of high plasma volume componentsO Gajic1, M Yilmaz1, R Iscimen1, D Kor1, J Winters1, B Afessa2, J Farmer1 1Mayo Clinic, Rochester, MN, USA; 2Mayo Clinic College of Medicine, Rochester, MN, USA Essential Care 2007, 11(Suppl 2):P410 (doi: ten.1186/cc5570) Objective To cut down the incidence of transfusion-related acute lung injury (ALI), PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/2075417 the American Association of Blood Banks (AABB) has not too long ago recommended speedy implementation of get STAT5-IN-1 approaches toSAvailable on line http://ccforum.com/supplements/11/Sobserved and all these patients had preT SvcO2 > 70 . While there was no important correlation amongst a worsening in SvcO2 and preT Hb, eight of these sufferers were allocated to Group 1. One more 13 transfusions have been completed using a SvcO2 preT < 70, and 10 of them improved (> five ) soon after transfusion (mean percentage of improvement = 18.9 ). Only 4 of those sufferers were allocated to Group 1. Patients with high levels of preT LAC (n = 21) only enhanced (reduction > 10 ) in 42.9 of instances. A total 53.3 of individuals with typical preT LAC levels worsened (increasing > 10 ) postT. The mean preT Hb from these individuals was eight.18 ?0.9. Conclusion In individuals with SvcO2 < 70 and/or Hb < 7.0 g/dl, transfusion seems to result in an improvement of perfusion parameters. However, in patients with SvcO2 > 70 or normal lactate levels, transfusion appears to impair tissue perfusion.P413 National survey of transfusion practicesN Frikha, R Ouezini, T Mestiri, M Bechikh, M Mebazaa, M Ben Ammar Mongi Slim Hospital, La Marsa, Tunisia Important Care 2007, 11(Suppl 2):P413 (doi: ten.1186/cc5573) Introduction The awakening on the residual risks of blood transfusion leads, everywhere inside the world, to efforts to reduce them. The aim of the study was to assess the transfusion practices in Tunisia. Patients and solutions A multicentric potential observational study of about 1,000 transfusions practiced through 2004 in Tunisia. Data have been determined by the prescriptor with the transfusion. The data were analyzed with SPSS 12.0. Results The imply age in the transfused sufferers was 35.78 years. The sex ratio was 1.two. A total of 48.3 of your patients had transfusion history. Allogeneic immunization and viral serology conversion had been reported in two.1 of these patients. The indications had been frequently carried in front of chronic medical pathologies (36.9 ), acute health-related pathologies (28.two ) and surgical pathologies (elective 11.7 , urgent 11.2 ). The haemoglobin threshold for transfusion was 7.29 g/dl and depended around the indication on the red cell transfusion: 6.16 g/dl for urgent health-related pathologies, 6.22 g/dl for chronic health-related pathologies, 7.74 g/dl for urgent surgical pathologies, ten.38 g/dl for elective surgery, 6.15 g/dl for urgent obstetrical pathologies. The imply platelet count was 24,000 (patients transfused by platelet units). The ABO and rhesus determination were produced in 99 from the situations. A phenotypic determination was required in only 34.five in the instances. The look for irregular agglutinins was created in 20.7 from the circumstances. The test of compatibility at the laboratory was practiced in 95.four of the situations. The level of blood transfused was two units. Immediate incidents had been reported in two.five on the cases. The posttransfusion haemoglobin average was of 9.15 g/dl. Discussion and conclusion The evolution in the blood transfusion was outstanding, since the use of total bloo.