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NameRamucirumabCAS NO.947687-13-0TypeWhole antibodySourceHumanTargetVEGFR2 (KDR)CloneMonocloneMolecular Weight147 kDaFormulaC6374H9864N1692O1996S46Antibody FormPurified immunoglobulinPhysical FormSolutionPlace of OriginUSAStorageSealed and stored at -70±15℃, away from light

2mg/tube, 5mg/tube, 10mg/tube, 20mg/tube

This product is the biosimilar of Ramucirumab (947687-13-0), which is a recombinant human IgG1 monoclonal antibody that specifically binds to vascular endothelial growth factor receptor 2. The biosimilar has an approximate molecular weight of 147 kDa, which is produced in genetically engineered mammalian CHO cells.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: bet-bromodomain.