E2012

Product Name: E2012
Description: E2012 is a γ-secretase modulator (GSM). E2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E2012 induces cataract in the rat by inhibiting DHCR24 at the final step of cholesterol synthesis with assoc
CAS NO: 1334493-07-0 Product: BP-1-102
Synonym: E2012; E-2012; E 2012.
IUPAC Chemical Name: (S,E)-1-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene)piperidin-2-one
In ChiKey: PUOAETJYKQITMO-LANLRWRYSA-NDYRK inhibitors
SMILE Code: O=C1N([[email protected]](C2=CC=C(F)C=C2)C)CCC/C1=CC3=CC=C(N4C=C(C)N=C4)C(OC)=C3
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22117884
Chemical Formula:C25H26FN3O2
ExactMass: 419.2009
Molecular Weight: 419.5004
Elemental Analysis: C, 71.58; H, 6.25; F, 4.53; N, 10.02; O, 7.63

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