Product Name: EBI-907
Description: EBI-907 is a highly potent and orally efficacious B-RafV600E inhibitor. EBI-907 displays a low single-digit nanomolar activity (IC50 = 4.9 nM), which is >10-fold more potent than Vemurafenib (IC50 = 59 nM). EBI-907 also exhibits high potency in select
CAS NO: 289480-64-4 Product: Treprostinil (sodium)
Synonym: EBI-907; EBI 907; EBI907; CAS# 1581764-31-9
IUPAC Chemical Name: N-(2-chloro-3-(1-cyclopropyl-8-methoxy-3H-pyrazolo[3,4-c]isoquinolin-7-yl)-4-fluorophenyl)-3-fluoropropane-1-sulfonamide
In ChiKey: TGF-beta_Smad inhibitors
SMILE Code: COC1=CC2=C(C=C1C3=C(F)C=CC(NS(CCCF)(=O)=O)=C3Cl)C=NC4=C2C(C5CC5)=NN4
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22118752
Chemical Formulaļ¼šC23H21ClF2N4O3S
ExactMass: 506.0991
Molecular Weight: 506.95
Elemental Analysis: C, 54.49; H, 4.18; Cl, 6.99; F, 7.50; N, 11.05; O, 9.47; S, 6.32