DAP-81

Product Name: DAP-81
Description: DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in
CAS NO: Product: GHRP-2 metabolite 1
Synonym: DAP81; DAP 81; DAP-81.
IUPAC Chemical Name: N-(4-((4-((2-benzoylphenyl)amino)-5-nitropyrimidin-2-yl)amino)phenyl)acetamide.
In ChiKey: GSK-3 inhibitors
SMILE Code: CC(NC1=CC=C(NC2=NC=C([N+]([O-])=O)C(NC3=CC=CC=C3C(C4=CC=CC=C4)=O)=N2)C=C1)=O
Appearance: white solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22117162
Chemical Formulaļ¼šC25H20N6O4
ExactMass: 468.1546
Molecular Weight: 468.4641
Elemental Analysis: C, 64.10; H, 4.30; N, 17.94; O, 13.66

About author

Leave a reply

You must be logged in to post a comment.