Danirixin

Product Name: Danirixin
Description: Danirixin, also known as GSK1325756, is a potent, high-affinity, selective and reversible CXCR2 antagonist in development for treatment of chronic obstructive pulmonary disease. The dose-dependent inhibition of agonist-induced neutrophil activation follo
CAS NO: 1857417-13-0 Product: MI-503
Synonym: GSK1325756; GSK-1325756; GSK 1325756; Danirixin
IUPAC Chemical Name: (S)-1-(4-chloro-2-hydroxy-3-(piperidin-3-ylsulfonyl)phenyl)-3-(3-fluoro-2-methylphenyl)urea
In ChiKey: NGYNBSHYFOFVLS-LBPRGKRZSA-NKeap1-Nrf2 inhibitors
SMILE Code: ClC(C(S([[email protected]]1CCCNC1)(=O)=O)=C2O)=CC=C2NC(NC3=CC=CC(F)=C3C)=O
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22117046
Chemical Formulaļ¼šC19H21ClFN3O4S
ExactMass: 441.0925
Molecular Weight: 441.9024
Elemental Analysis: C, 51.64; H, 4.79; Cl, 8.02; F, 4.30; N, 9.51; O, 14.48; S, 7.25

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