E7449

Product Name: E7449
Description: E7449 is an orally available small molecule inhibitor of the nuclear enzymes poly (ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration, E7449 selectively binds to PARP 1 and 2, thereby preventing the repair o
CAS NO: 1141777-14-1 Product: Emixustat
Synonym: E7449; E 7449; E-7449
IUPAC Chemical Name: 8-(isoindolin-2-ylmethyl)-2H-pyridazino[3,4,5-de]quinazolin-3(9H)-one
In ChiKey: JLFSBHQQXIAQEC-UHFFFAOYSA-NHedgehog inhibitors
SMILE Code: O=C1NN=C(N2)C3=C(C=CC=C31)N=C2CN(C4)CC5=C4C=CC=C5
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22118468
Chemical Formulaļ¼šC18H15N5O
ExactMass: 317.12766
Molecular Weight: 317.34
Elemental Analysis: C, 68.13; H, 4.76; N, 22.07; O, 5.04

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