Product Name: Edatrexate
Description: Edatrexate is a polyglutamatable folate antagonist analogue of methotrexate with antineoplastic activity. Edatrexate inhibits dihydrofolate reductase, thereby increasing cellular levels of polyglutamates, inhibiting thymidylate synthase and glycinamide ri
CAS NO: 1190932-38-7 Product: COH29
Synonym: 10-ethyldeazaaminopterin; 10-EDAM; CGP30694; CGP 30694; Edatrexate.
IUPAC Chemical Name: (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)butan-2-yl]benzoyl]amino]pentanedioic acid
In ChiKey: FSIRXIHZBIXHKT-MHTVFEQDSA-Nscreening-libraries inhibitors
SMILE Code: O=C(O)[[email protected]@H](NC(C1=CC=C(C(CC)CC2=NC3=C(N)N=C(N)N=C3N=C2)C=C1)=O)CCC(O)=O
Appearance: white solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress.com
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22119161
Chemical Formulaļ¼šC22H25N7O5
ExactMass: 467.19172
Molecular Weight: 467.4778
Elemental Analysis: C, 56.52; H, 5.39; N, 20.97; O, 17.11

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