Product Name: E-6123
Description: E-6123 is a platelet activating factor inhibitor potentially for the treatment of asthma. E6123 inhibited PAF inhalation-induced bronchoconstriction in guinea pigs with an ED50 value (p.o.) of 1.3 micrograms/kg which was lower than those of other PAF-anta
CAS NO: 198474-05-4 Product: PF-06840003
Synonym: E-6123; E 6123; E6123.
IUPAC Chemical Name: (S)-(6-(2-chlorophenyl)-1,4-dimethyl-7,10-dihydro-4H-pyrido[4,3:4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-9(8H)-yl)(cyclopropyl)methanone
In ChiKey: Syk inhibitors
SMILE Code: O=C(N(C1)CCC2=C1SC3=C2C(C4=CC=CC=C4Cl)=N[[email protected]@H](C)C5=NN=C(C)N53)C6CC6
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22118314
Chemical Formulaļ¼šC23H22ClN5OS
ExactMass: 451.1234
Molecular Weight: 451.973
Elemental Analysis: C, 61.12; H, 4.91; Cl, 7.84; N, 15.50; O, 3.54; S, 7.09