G-479

Product Name: G-479
Description: G-479 is an potent MEK inhibitor. Structurally, G-479 is an analogue of GDC-0623 (or so-call Me-Too drug). G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects.
CAS NO: 99-50-3 Product: Protocatechuic acid
Synonym: G479; G-479; G 479.
IUPAC Chemical Name: (R)-N-(2,3-dihydroxypropoxy)-5-((2-fluoro-4-iodophenyl)amino)imidazo[1,5-a]pyrazine-6-carboxamide
In ChiKey: PKD inhibitors
SMILE Code: O=C(C1=C(NC2=CC=C(I)C=C2F)N3C(C=N1)=CN=C3)NOC[[email protected]](O)CO
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site click
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22121220‎
Chemical Formula:C16H15FIN5O4
ExactMass: 487.01528
Molecular Weight: 487.22
Elemental Analysis: C, 39.44; H, 3.10; F, 3.90; I, 26.05; N, 14.37; O, 13.14