G-573

Product Name: G-573
Description: G-573 is an allosteric inhibitor of MEK that is both potent and selective. The IC(50) value for pERK inhibition in HCT116 tumours by G-573 was estimated to be 0.406  µM. The IC(50) values for tumour growth inhibition in HCT116 and H2122 were estimated to
CAS NO: 99746-73-3 Product: L-Praziquanamine
Synonym: G573; G-573; G 573.
IUPAC Chemical Name: 2-(3-chlorophenyl)-1H-benzo[d]imidazole
In ChiKey: Survivin inhibitors
SMILE Code: ClC1=CC(C2=NC3=CC=CC=C3N2)=CC=C1
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22121242
Chemical Formula:C13H9ClN2
ExactMass: 228.04543
Molecular Weight: 228.68
Elemental Analysis: C, 68.28; H, 3.97; Cl, 15.50; N, 12.25