Product Name: JH295
Description: JH295 is an irreversible, cysteine-targeted inhibitors of the human centrosomal kinase, Nek2. JH295 irreversibly inhibited cellular Nek2 without affecting the mitotic kinases, Cdk1, Aurora B, or Plk1. Moreover, JH295 did not perturb bipolar spindle assemb
CAS NO: 150145-89-4 Product: (S)-MCPG
Synonym: JH295; JH 295; JH-295
IUPAC Chemical Name: (Z)-N-(3-((2-ethyl-4-methyl-1H-imidazol-5-yl)methylene)-2-oxoindolin-5-yl)propiolamide
SMILE Code: C#CC(NC1=CC2=C(NC(/C2=CC3=C(C)N=C(CC)N3)=O)C=C1)=O
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site:Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22127588
Chemical Formula:C18H16N4O2
ExactMass: 320.12733
Molecular Weight: 320.35
Elemental Analysis: C, 67.49; H, 5.03; N, 17.49; O, 9.99