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Product Name: R547
Description: R547 is orally bioavailable diaminopyrimidine cyclin-dependent kinase inhibitor (CDKI) with potential antineoplastic activity. CDKI R547 selectively binds to and inhibits CDKs, especially CDK1/cyclin B, CDK2/cyclin E, and CDK4/cyclin D1. The inhibition of
CAS NO: 103656-40-2 Product: Calcitriol Impurities D
Synonym: R547; R 547; R-547; Ro4584820; Ro-4584820; Ro 4584820.
IUPAC Chemical Name: (4-amino-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone
In ChiKey: Sirtuin inhibitors
SMILE Code: O=C(C1=CN=C(NC2CCN(S(=O)(C)=O)CC2)N=C1N)C3=C(OC)C=CC(F)=C3F
Appearance: Solid powder
Purity: 98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Web Site:Medchemexpress
Storage Condition: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: 2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 – 4 C for short term (days to weeks), or -20 C for long term (months).PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22142891
Chemical Formula:C18H21F2N5O4S
ExactMass: 441.12823
Molecular Weight: 441.45
Elemental Analysis: C, 48.97; H, 4.79; F, 8.61; N, 15.86; O, 14.50; S, 7.26

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Author: bet-bromodomain.